Andrew Blauvelt, MD, MBA, a dermatologist at the Oregon Medical Research Center in Portland, Oregon, reviews the effect of ruxolitinib cream on itch in patients with atopic dermatitis, including the mechanism of action of this effect, along with two recent studies published in the Journal of the American Academy of Dermatology1 and Journal of the European Academy of Dermatology and Venereology2 that have investigated improvements in itch with ruxolitinib.
References
1. Blauvelt A, Szepietowski JC, Papp K, et al. Itch-free state in patients with atopic dermatitis treated with ruxolitinib cream: A pooled analysis from two randomized phase 3 studies. J Am Acad Dermatol. 2022 Sep 14;S0190-9622(22)02688-3.
2. Blauvelt A, Kircik L, 2, Papp KA, et al. Rapid pruritus reduction with ruxolitinib cream treatment in patients with atopic dermatitis. J Eur Acad Dermatol Venereol. 2023 Jan;37(1):137–146.
Itch-free state in patients with atopic dermatitis treated with ruxolitinib cream: A pooled analysis from two randomized phase 3 studies
Rapid pruritus reduction with ruxolitinib cream treatment in patients with atopic dermatitis
